Avtor/Urednik		Slivnik, Matej
Naslov		Uporaba dolgodelujočih agonistov beta2 pri otrocih astmatikih
Prevedeni naslov		Use of long-acting beta2 agonists in children with asthma
Tip		članek
Vir		Zdrav Vars
Vol. in št.		Letnik 37, št. Suppl
Leto izdaje		1998
Obseg		str. 187-9
Jezik		slo
Abstrakt		Asthma is the most frequent chronic disease among children. Modern treatment is based on the knowledge that its essence is chronic inflammation of the respiratory paths. long-acting beta2 agonists are powerful bronchodilation medicaments with a prolonged effect. In line with Slovenian guidelines, we use them for additional treatment of severe forms of asthma. They are very effective in preventing exertion-induced asthma. Although a final assessment of their comprehensive use can not be made at this point, we may - with a fair degree of doubt - contemplate their use also in treating symptoms of nocturnal asthma and asthmatic symptoms which occur despite treatment with low dosages of inhalationcorticosteroids. We must caution that long-acting beta2 agonists, as a medicament used on its own, are inappropriate for treating acute aggravation of asthma and should be given, under the diligent supervision of a doctorexperienced in asthma treatment, only to on aware and properly educated patint. We must not forget that treating asthma is not a schematic ad hoc method of solving the difficulties but an individual and comprehensive treatment for a patient in which - despite the progress of science - new questions and dilemmas continue to occur.
Izvleček		Astma je najpogostnejše kronično obolenje pri otrocih. Sodobno zdravljenje temelji na spoznanju, da je njena osnova kronično vnetje dihalnih poti. Dolgodelujoči agonisti beta2 so močna bronhodilatacijska zdravila z dolgotrajnim učinkom. Glede na slovenske smernice jih uporabljamo pri dodatnem zdravljenju hudih oblik astme. Zelo učinkoviti so za preprečevanje astme med naporom. Čeprav končne presoje o njihovi celoviti uporabi še ni mogoče podati, lahko - sicer z določenim dvomom - razmišljamo tudi o njihovi uporabi pri zdravljenju simptomov nočne astme in astmatičnih simptomov, ki se pojavljajo kljub zaščiti z nizkimi odmerki inhalacijskih kortikosteroidov. Ob tem se moramo zavedati, da dolgodelujoči agonisti beta2 kot edino zdravilo niso primerni za zdravljenje akutnih poslabšanj astme in da sodijo ob vestnem nadzoru zdravnika, ki dobro obvlada zdravljenje astme, le v roke osveščenega in dobro poučenega astmatika. Ne smemo poabiti, da vodenje astme ni shematski ad hoc način reševanja težav, temveč individualna in celostna obravnava bolnika, pri kateri se - kljub napredku znanosti - še vedno pojavljajo nova vprašanja in dileme.
Deskriptorji		ASTHMA ADRENERGIC BETA-AGONISTS CHILD DELAYED-ACTION PREPARATIONS