Avtor/Urednik		Lotrič-Furlan, Stanka
Naslov		Uzroci febrilnih bolesti poslije uboda krpelja
Tip		monografija
Kraj izdaje		Zagreb
Založnik		Sveučilište u Zagrebu, Medicinski fakultet
Leto izdaje		1998
Obseg		str. 92
Jezik		cro
Abstrakt		130 patients with a febrile illness occuring within six weeks after a tick bite wer included in a prospective study, performed at the Department of Infectious Diseases, University Medical Centre, Ljubljana, Slovenia, from March 1995 until December 1996. The aim of this study was to test thehypothesis that in addition to Lyme borreliosis and tick-borne meningoencephalitis (TBE), infections caused by Ehrlichiae and spotted fever group Rickettsiae are also rpesent in Slovenia. All the patients were tested for the presence of serum antibodies against TBE virus, B. burgdorferi sensu lato, R, conorii and human monocytic and granulocytic erhlichiae. The cause of the febrile illness remained unexplained in a half (50%) of the patients included in the study. In 36 (27.7%) out of 130 patients IgM antibodies against TBE virus were detected. All these patients had meningitis or meningoencephalitis; 12 of them were examined not only in the second phase but also in the first phase of their illness. In 23 (63.9%) out of 36 patients only acute TBE infection was confirmed, in six (16.7%) patients borrelial serum IgM and/or IgG antibodies in titer >- 1: 256 were also found, and in another seven patients IgG antibody serum titers >- 1:128 against human granulocytic erhlichiae (HGE) were detected in addition to borrelial and TBE antibodies. In 18.5% (24/130) patients IgM and/or IgG antibodies against B. burgdorferi in a titer >- 1:256 were detected by indirect immunofluorescent assay without absorbtion. In two patients with proven Lyme borreliosis serum borrelial antibodies were negative. In six (25%) patients in whom positive borrelial antibody titers were present, a simultaneous acute infection with TBE virus was found. namely, three patients revealed concomitant acute infectionwith TBE virus and neuroboreliosis proven by the production of intrathecal antibodies against B. burgdorferi (IgG index > 2).(Abstract truncated at 2000 characters)
Deskriptorji		FEVER TICKS BITES AND STINGS LYME DISEASE ENCEPHALITIS, TICK-BORNE EHRLICHIOSIS ENCEPHALITIS VIRUSES, TICK-BORNE EHRLICHIA BORRELIA BURGDORFERI ANTIBODIES, VIRAL IGG IGM