Author/Editor     Godić, Aleksandar
Title     Analiza površine las pri bolnikih z ichthyosis vulgaris
Translated title     Analysis of hair surface in patients with ichthyosis vulgaris
Type     monografija
Place     Ljubljana
Publisher     Medicinska fakulteta
Publication year     1999
Volume     str. 38
Language     slo
Abstract     Introduction. Ichthyoses are a group of hereditary disorders characterized by generalized persisting scaling, but caused by different pathogenetic mechanisms. Other ectodermal structures such as nails and hair may be affected beside possible noncutaneous manifestations. The aim of the study was to evaluate cuticular cells disorders (CD) of hair shafts of patients with ichthyosis vulgaris (IV). Materials And Methods. We examined the hair samples of 12 patients with ichthyosis vulgaris (IV), (6 males, 6 females, aged from 2 to 16 years) by means of Scanning Electron Microscope. The hair shafts were cut just above the follicular ostia in occipital region, frontal region and from scaly regiones when existed. We examined proximal 10 mm long parts of each of the hair, each of one was taken from the examined regions. Two helthy subjects were considered as control group. Results and Conclusions The surface of examined hair in patients with IV revealed different changes of hair cuticle ranged from nearly normal to extremely damaged. In 3 cases we found pili torti. On the hair surface in patients with IV we observed transversal and vertical fissures and areas with exposed granular endocuticle.
Descriptors     ICHTHYOSIS VULGARIS
HAIR
HAIR FOLLICLE