Avtor/Urednik		Pauluzzi, P; Doria, A; Nobile, C; Trevisan, G
Naslov		Calcipotriol cream in childhood psoriasis
Tip		članek
Vir		Acta Dermatovenerol Alp Pannon Adriat
Vol. in št.		Letnik 8, št. 3
Leto izdaje		1999
Obseg		str. 119-21
Jezik		eng
Abstrakt		Background. Calcipotriol ointment, a vitamin D3 synthetic derivative, confirmed its efficacy and its high safety when employed in the treatment of adult psoriasis and sometimes in children, too. Cream seems to be the most clinically appropriate choice to treat particularly delicate and easily irritable skins. Methods. Nine enrolled psoriatic children (mean age 10.1 + 4.1 SD years) were treated with calcipotriol cream (50 ug/g) 2 application/day during six consecutive weeks. PASI (Psoriasis Area and Severity Index) was evaluated at fortnightly visits. Furthermore, routine laboratory parameters were controlled before and at the end of the treatment. Results. Mean PASI was 2.2+0.5 (SEM) at the baseline, and decreased to 0.7+0.5 after six weeks of treatment; a 65.9% reduction was seen. Calcipotriol cream showed an excellent safety, as the lack of irritant cutaneous adverse reactions and/or laboratory parameters alterations. Conclusion. Our clinical experience suggests Calcipotriol cream as one of the most important therapeutic choice in psoriasis.
Deskriptorji		PSORIASIS CHOLECALCIFEROL CHILD OINTMENTS TREATMENT OUTCOME