| Author/Editor | Lotrič-Furlan, Stanka; Cimperman, Jože; Maraspin, Vera; Ružić-Sabljić, Eva; Logar, Mateja; Jurca, Tomaž; Strle, Franc | |
| Title | Lyme borreliosis and peripheral facial palsy | |
| Type | članek | |
| Source | Wien Klin Wochenschr | |
| Vol. and No. | Letnik 111, št. 22-23 | |
| Publication year | 1999 | |
| Volume | str. 970-5 | |
| Language | eng | |
| Abstract | From 1994 to 1996, 114 consecutive patients older than 15 years who presented at the Department of Infectious Diseases, University Medical Centre, Ljubljana, fulfilled the criteria for inclusion into this study on the borrelial aetiology of peripheral facial palsy (PFP). The study was restricted to patients without a conceivable explanation for their PFP, erythema migrans or history of erythema migrans, clinical signs/symptoms of frank meningitis or any other neuro-logical manifestation in addition to PFP. In 22 (19.3%) of these 114 patients borrelial infection was confirmed by one of the following: in 3 (13.6%) by the isolation of Borrelia burgdorferi sensu lato from cerebrospinal fluid (CSF), in 11 (50%) by the presence of intrathecal anti-body production, and in 8 (36.4o/a) by seroconversion to borrelial antigens. Additional 20 (17.5%) patients interpreted as having had a probable borrelial infection, had positive (? 1:256) IFA IgM and/or IgG borrelial serum antibody titres, and in 9 (7.9%) patients borderline borrelial antibody titres (1:128) were found (interpreted as a possible infection). In 63 (55.3%) patients the serological tests remained negative. Lymphocytic pleocytosis was found at the first visit in 12/22 (54.5%) patients with confirmed borrelial infection, in 3/20 (15%) with probable infection, in 1/9 (11.1%) with possible infection, and in 10/63 (15.9%) patients with symptoms of unknown aetiology. Patients with confirmed borrelial infection had abnormal CSF findings significantlly more often than did patients with symptoms of unknown aetiology (p = 0.0139 for lymphocytic pleocytosis and/or elevated CSF protein levels, and p = 0.0010 for lymphocytic pleocytosis). Local and systemic signs/-symptoms were also more common in patients with confirmed borrelial infection than in those with an symptoms of unknown aetiology (p = 0.0258). (Abstract truncated at 2000 characters.) | |
| Descriptors | LYME DISEASE BORRELIA BURGDORFERI NEUROLOGIC MANIFESTATIONS CEREBROSPINAL FLUID IGM IGG MENINGITIS, BACTERIAL FACIAL PARALYSIS CRANIAL NERVE DISEASES NEURITIS |