Avtor/Urednik		Rupreht, Ruth Rebeka; Faas, Brigitte Henrica Wilhelmina; Bojanič, Vesna; van Wijk, Petra Anna Maaskant; Glonar, Ljerka; Bricl, Irena; Rožman, Primož; Čurin-Šerbec, Vladka
Naslov		Rhd and C/cE/e genotyping in Slovenian population
Tip		članek
Vir		Pflugers Arch
Vol. in št.		Letnik 439, št. 3 Suppl
Leto izdaje		2000
Obseg		str. R58-9
Jezik		eng
Abstrakt		The Rhesus (Rh) blood group system is, after ABO, clinically most important. Alloantibodies directed against Rh antigens are the major cause of a haemolytic disease of newborn (HDN) and of transfusion reactions. In search for novel methods for Rh genotyping we started to compare Rh genotypes identified from different tissues and Rh phenotypes. Genotypes determined from blood samples with PCR based RhD, C/c and E/e genotyping methods were compared with serologically identified phenotypes (N=32). With two exceptions the results of phenotyping and genotyping were in concordance. Two Rh serotypes from a Slovenian family that were unexpected according to the Mendelian laws were characterised genotypically. The two family members were suspected to have a chromosomal deletion on RH gene locus.
Deskriptorji		RH-HR BLOOD-GROUP SYSTEM BLOOD DONORS POLYMERASE CHAIN REACTION