Author/Editor		Sočan, Maja; Vidmar, Ludvik
Title		Povzročitelji zunajbolnišničnih pljučnic pri odraslih
Translated title		Microbial etiology in community - acquired pneumonia in adults
Type		članek
Source		Krka Med Farm Supl
Vol. and No.		Letnik 20, št. Suppl 2
Publication year		1999
Volume		str. 57-65
Language		slo
Abstract		211 adult patients hospitalised in the Department for Infectious Diseases in Ljubljana with community/acquired pneumonia were studied prospectively to determine the microbial etiology of pneumonia in the period between April 1996 and the March 1997. Blood culture was positive in 23 patients.Streptococcus pneumoniae was the most frequently isolated bacteria. Chlamydia pneumoniae pneumonia was confirmed serologically in 18% of the patients. Antibodies confirming acute Mycoplasma pneumoniae, Legionella, Chlamydia psittaci and Coxiella burnetii infection were found in a lower number of patients. Acute viral infection was confirmed in 51 (24%) patients, influenza A virus was most frequently identified. Viral serological tests and tests used to diagnose legionellosis were compared and their sensitivity and specificity studied. Discriminant analysis was used to identify those variables which are correlated with typical bacterial pneumonia caused by Chamydia pneumoniae.
Summary		Pri 211 odraslih bolnikih, ki so bili zaradi pljučnice, pridobljene v domačem okolju, na Kliniko za nalezljive bolezni in vročinska stanja v Ljubljani sprejeti od aprila 1996 do marca 1997, smo naredili številne mikrobiološke preiskave za odkritje bakterijskih in virusnih povzročiteljev pljučnice. Pri 23 bolnikih smo izolirali bakterijo iz krvi, največkrat Streptococcus pneumoniae. Serološko smo pri 18% bolnikov dokazali Chlamydio pneumoniae, redkeje legionelozo ali pljučnico, ki so jo povzročile Mycoplasma pneumoniae, Chlamydia psittaci ali Coxiella burnentii. Enainpetdeset bolnikov(24 %) je imelo virusno okužbo, največkrat jo je povzročil virus gripe A. Primerjali smo serološke preiskave, s katerimi dokazujemo virusne okužbe, in okužbo z legionelami ter izračunali njihovo občutljivost in specifičnost. S pomočjo modela diskriminantne analize smo skušali identificirati spremenljivke, ki razlikujejo med seboj klasične bakterijske, netipične pljučnice, ki jih je povzročila Chlamydia pneumoniae.
Descriptors		PNEUMONIA COMMUNITY-ACQUIRED INFECTIONS HOSPITALIZATION ADULT SERODIAGNOSIS PNEUMONIA, BACTERIAL PNEUMONIA, VIRAL