Avtor/Urednik		Krachler, M; Rossipal, E; Micetič-Turk, D
Naslov		Concentrations of trace elements in arterial and venous umbilical cord sera
Tip		članek
Vir		Trace Elem Electroly
Vol. in št.		Letnik 16, št. 1
Leto izdaje		1999
Obseg		str. 46-52
Jezik		eng
Abstrakt		Aims, material and methods: Inductively coupled plasma mass spectrometry was applied to the determination of the 19 trace elements Ba, Be, Bi, Ca, Cd, Cs, Cu, La, Li, Mg, Mn, Mo, Pb, Rb, Sb, Sn, Sr, Tl, and Zn in a total of 38 umbilical cord sera (UCS) of healthy newborns. Nine pairs of arterial and venous as well as 20 mixed UCS have been analyzed. Two whole blood and two serum reference materials have been employed to ensure the accuracy and precision of the applied analytical procedure. Good agreement between certified and experimental concentrations could be obtained. Results: Based on the medians, concentrations of the essential elements in all arterial UCS were lower compared to the corresponding venous UCS by 2.5% for Ca, 4% for Zn, 5% for Mg, 10% for Cu, 14% for Mn and Mo. For most of the non essential and toxic elements equal (Be, Bi, Cd, Cs, La, Li, Sb, Tl) or slightly higher (Pb, Rb, Sr) concentrations in venous UCS compared to arterial UCS were determined. Only for Ba were definite higher concentrations in arterial UCS found. The concentrations of most of the trace elements (Cd, Cs, La, Mg, Mo, Pb, Rb, Sb, Sr, Tl, and Zn) in UCS coincided well with the reference ranges for healthy adults. Conclusion: However, UCS concentrations for Ca and Mn were distincly higher and for Cu significatly lower compared to sera of healthy adults. Therefore, it is quite evident that these elements are "consumed" by the fetus during pregnancy.
Deskriptorji		TRACE ELEMENTS FETAL BLOOD INFANT, NEWBORN UMBILICAL ARTERIES UMBILICAL VEINS SPECTRUM ANALYSIS, MASS QUALITY CONTROL