Author/Editor		Gnidovec, Barbara
Title		Aktimetrska analiza cirkadianega ritma budnosti in spanja v prvih šestih mesecih življenja
Type		monografija
Place		Ljubljana
Publisher		Medicinska fakulteta
Publication year		2000
Volume		str. 45
Language		slo
Abstract		Actigraphy enables continuous activity recording for prolonged periods. Body motility data provide useful measures of sleep-wake (S/W) rhythm. The aim of our study was to examine the validity of the actigraphy for the assessment of S/W rhythm during the first six months of life. Assessment of the development of S/W rhythm is important for early detection of disorders of the central nervous system. It was hypothesized that actigraphy is a useful tool for the evaluation of S/W rhythm in infants. Therefore a scoring algorithm for automatic identification of S/W states was developed. We wanted to determine whether actigraphic data alone could provide a valid distinction between active and quiet sleep. By continuous activity monitoring development of S/W rhythm in the first six months of life was evaluated. Ten healthy infants were studied at one, three and six months of age. On each occasion continuous 72-hour actigraphic recording was performed. During actigraphy infants' behavioral states were observed in a total period of three hours. Concomitant actigraphic and observation data were matched on 10-s epoch-by-epoch basis. Discriminant function analysis was used to develop an algorithm for S/W state determination in three- and six-month-old infants. In one-month-old infants no such algorithm could be made due to the relative insensitivity of the actigraph used. Reliable actigraphic distinction of active and quiet sleep could not be made in any of the age groups. Using algorithm all actigraphic data was scored for S/W states. The chi-square periodogram analysis was used to estimate periodic components of S/W rhythm. It revealed that circadian influence on S/W rhythm is present already by the end of the first month. Actigraphy was found to be a simple and non obtrusive method for the evaluation of S/W rhythm in infants. The actigraph used in our study provides valid S/W distinction during three and six months of age. (Abstract truncated at 2000 characters)
Descriptors		SLEEP WAKEFULNESS MOVEMENT CIRCADIAN RHYTHM INFANT POLYSOMNOGRAPHY