Author/Editor		Turel, Iztok; Šonc, Andrej; Zupančič, Marija; Sepčić, Kristina; Turk, Tom
Title		Biological activity of some magnesium(II) complexes of quinolones
Type		članek
Source		Met-Based Drug
Vol. and No.		Letnik 7, št. 2
Publication year		2000
Volume		str. 101-4
Language		eng
Abstract		A new magnesium complex of quinolone antibacterial agent was prepared. This new complex as well as a previously isolated complex of magnesium with ciprofloxacin were tested against various Gram positive and Gram negative microorganisms. Antimicrobial activities were evaluated using the agar diffusion test. The results have shown that all magnesium complexes are significantly less active than the parent quinolone drugs. It was also found that the activity of quinolones is reduced when the solutions of quinolones are titrated with magnesium ions.
Descriptors		QUINOLONES MAGNESIUM MICROBIAL SENSITIVITY TESTS CIPROFLOXACIN COLONY COUNT, MICROBIAL