Avtor/Urednik		Peharda, V; Gruber, F; Kaštelan, M; Brajac, I; Čabrijan, L
Naslov		Pruritus an important symptom of internal diseases
Tip		članek
Vir		Acta Dermatovenerol Alp Pannon Adriat
Vol. in št.		Letnik 9, št. 3
Leto izdaje		2000
Obseg		str. 92-104
Jezik		eng
Abstrakt		Pruritus is a common unpleasant sensation, accompanied frequently by scratching. This symptom can be caused by numerous cutaneous diseases and by internal disorders. Pruritus is mediated by histamine, proteases, prostaglandins, and substance P. The biochemical, cellular mechanisms and the neuroanatomical pathway which determine the outbreak of pruritus in different internal diseases are described. The exact diagnosis is important for choosing an appropriate treatment.
Deskriptorji		PRURITUS INTERNAL MEDICINE UREMIA CHOLESTASIS NEOPLASMS HISTAMINE PROSTAGLANDINS SUBSTANCE P