Avtor/Urednik		Kuzman, Drago; Žnidarčič, Tadej; Gros, Marjan; Vrhovec, Sonja; Svetina, Saša; Žekš, Boštjan
Naslov		Effect of pH on red blood cell deformability
Tip		članek
Vir		Pflugers Arch
Vol. in št.		Letnik 440, št. 5 Suppl
Leto izdaje		2000
Obseg		str. R193-4
Jezik		eng
Abstrakt		The effect of pH on the red blood cell (RBC) deformability, which is a consequence of a change of cell membrane elastic properties is studied experimentally. With the intention to reduce the effects on deformability of cell geometry and cytoplasmic viscosity, we measured the deformability of the cells with the same volume at various pH of cell suspension from 6.2 to 8 0. Constant cell volume was achieved by varying osmolarity. Deformability was quantified by measuring the elongation of RBCs subjected to velocity gradient in a transparent cone-plate rheoscope. Observed significant decrease of deformability at lower pH leads to the conclusion that membrane elastic properties could be affected by pH changes in the range from 6.2 to 8.0.
Deskriptorji		ERYTHROCYTES ERYTHROCYTE DEFORMABILITY HYDROGEN-ION CONCENTRATION ERYTHROCYTE MEMBRANE VISCOSITY