| Avtor/Urednik | Noč, Marko; Weil, Max Harry; Tang, Wanchung; Sun, Shijie; Pernat, Andrej; Bisera, Joe | |
| Naslov | Electrocardiographic prediction of the success of cardiac resuscitation | |
| Tip | članek | |
| Vir | Crit Care Med | |
| Vol. in št. | Letnik 27, št. 4 | |
| Leto izdaje | 1999 | |
| Obseg | str. 708-14 | |
| Jezik | eng | |
| Abstrakt | Objecfives: To identify a method for predicting the success or failure of a defibrillatory shock such as to avoid potentiatly detrimental interruptions of cardiopulmonary resuscitation (CPR). Such a method would also guide more optimal programming of automated external defibrillators. Design: Prospective, observational animal study. Setting: Medical research laboratory in a university-affiliated research and educational foundation. Subjects: Domestic pigs. Interventions: Ventricular fibrillation (VF) was electrically in- duced in 66 domestic pigs. After an interval of between 3 and 5 mins of untreated VF, precordial compression was begun. Electro-cardiographic lead 2 was monitored and artifacts produced during precordial compression were removed by digital filtering. Measurements and Main Results: In the derivation study, electrical defibrillation restored spontaneous circulation in 30 of the 66 animals. Successfully resuscitated animals had significantiy greater coronary perfusion pressure, maximum VF amplitude, mean VF amplitude, and dominant VF frequency. No animals were resusci- tated if the coronary pertusion pressure was <8 mm Hg, maximum amplitude was <0.48 mV, mean amplitude was <0.25 mV, or dominanf frequency <9.9 Hz independently of the duration of untreated VF. When mean amplitude and dominant frequency were com- bined, the predictability was further improved. In an additional validation sfudy of 14 animals, consecutive defibrillations were uniformly unsuccessful if the combination of mean amplitude and dominant frequency did not exceed the threshold values obtained in derivation study. Conclusion: Mean VF amplitude alone or in combination with dominant frequency of VF was expressed as a numerical score. It served as an objective noninvasive measurement on a par with that of coronary pertusion pressure for predicting the success of defibrillation. (Abstract truncated at 2000 characters) | |
| Deskriptorji | CARDIOPULMONARY RESUSCITATION ELECTROCARDIOGRAPHY VENTRICULAR FIBRILLATION DISEASE MODELS, ANIMAL SWINE PREDICTIVE VALUE OF TESTS PROGNOSIS PROSPECTIVE STUDIES REPRODUCIBILITY OF RESULTS SEVERITY OF ILLNESS INDEX TREATMENT OUTCOME |