Avtor/Urednik		Pinter, Bojana
Naslov		Hormonska kontracepcija in metabolizem kosti
Prevedeni naslov		Hormonal contraception and bone metabolism
Tip		članek
Vir		Zdrav Vestn
Vol. in št.		Letnik 70, št. 1
Leto izdaje		2001
Obseg		str. 27-31
Jezik		slo
Abstrakt		Background. Sex hormones play the key role in bone gain and its maintenance. The influences of combined oral contraception and depo progestagens on metabolic processes have been thoroughly researched. However, their influence on bone metabolism has not been clarified yet. In the article the studies on influences of combined oral contraception and depo progestagens on the bone metabolism are summarized. Conclusions. Bone metabolism is decreased by the use of combined oral contraception. Decreased bone metabolism in adult and premenopausal women results in bone mass preservation, but the effect on bone mass in adolescence and young adulthood has not been clarified yet. Bone mass is decreased by the use of depo medroxyprogesteron acetat, but is not affected by the use of levonorgestrel subdermal implants.
Izvleček		Izhodišča. Spolni hormoni igrajo ključno vlogo pri pridobivanju in ohranjanju kostne mase. Vpliv kombinirane oralne hormonske kontracepcije (OHKC) in depo progestagenov na metabolične procese v telesu so že precej raziskani, še vedno pa ni popolnoma pojasnjen njihov vpliv na metabolizem kosti. V prispevku povzemamo rezultate raziskav o vplivu kombinirane OHKC in depo progestagenov na metabolizem kosti. Zaključki. Kombinirana OHKC zavira metabolizem kosti, kar pri odraslih in premenopavznih ženskah povzroči ohranjanje kostne mase, učinek na kostno maso v dobi odraščanja in v zgodnji odrasli dobi pa še ni povsem jasen. Uporaba depo medroksiprogesteron acetata zmanjša kostno maso, uporaba levenoregestrelnih podkožnih vsadkov pa na pridobivanje in vzdrževanje kostne mase ne vpliva.
Deskriptorji		CONTRACEPTIVES, ORAL, HORMONAL BONE DEMINERALIZATION, PATHOLOGIC BONE DENSITY OSTEOPOROSIS ESTROGENS PROGESTATIONAL HORMONES LEVONORGESTREL