| Avtor/Urednik | Zadravec, Darko; Kerč, Janez; Kristl, Julijana | |
| Naslov | Pregled gastrointestinalnih pospeševalcev absorpcije učinkovin | |
| Prevedeni naslov | Review of gastrointestinal drug absorption enchancers | |
| Tip | članek | |
| Vir | Farm Vestn | |
| Vol. in št. | Letnik 51, št. 4 | |
| Leto izdaje | 2000 | |
| Obseg | str. 535-46 | |
| Jezik | slo | |
| Abstrakt | In introduction absorption mechanisms in digestive tract are shortly presented, followed by review of gastrointestinal absorption enhancers used for peroral drug delivery, their status and the cited tested drugs. The information presented enables reliable choice of approproate absorption enhancers in combination with selected drug substance and pharmaceutical form. | |
| Izvleček | V prispevku so uvodoma predstavljeni mehanizmi absorpcije v prebavnem traktu, v nadaljevanju je podan pregled gastrointestinalnih pospeševalcev absorpcije uporabljanih pri peroralnem dajanju zdravilnih učinkovin in njihov status, navedene pa so tudi učinkovine, ki so bile z njimi testirane. Članek omogoča lažjo izbiro najučinkovitejšega pospeševalca absorpcije glede na izbrano učinkovino in farmacevtsko obliko. | |
| Deskriptorji | GASTROINTESTINAL SYSTEM INTESTINAL ABSORPTION GLYCERIDES FATTY ACIDS CELL MEMBRANE PERMEABILITY MEMBRANE FLUIDITY BILE ACIDS AND SALTS SURFACE-ACTIVE AGENTS CHELATING AGENTS |