Author/Editor		Liščić, RM; Mihelin, M
Title		Transcranial magnetic stimulation of the brain - applications in basic and clinical neuroscience
Type		članek
Source		Medicon 2001. 9th Mediterranean conference on medical and biological engineering and computing. 2nd Croatian-Slovenian meeting on biomedical engineering. 1st international conference on muscle fibre structure and function. 5th symposium of Croatian society for medical informatics (Medicine informatics 2001). Proccedings of the International federation for medical and biological engineering. Part 1, Part 2; 2001 Jun 12-15; Pula
Publication year		2001
Volume		str. 43-5
Language		eng
Abstract		Transcranial magnetic stimulation (TMS) is a safe, noninvasive, and painless tool to stimulate the motor cortex in behaving human subject. The utility of TMS in studying brain fuction has been demonstrated in diverse neuroscience applications. We present a summary of the applications of a single-pulse TMS in basic neuroscience and clinical work, paired-pulsed TMS, and compare it with a repetitive TMS (rTMS). rTMS, however, is a more powerful and potentially dangerous modality, capable of regionally bloclung or facilitating cortical processes. Modulation of cortical excitability by rTMS has therapeutic potential in psychiatric and neurological disorders. TMS is still a relatively young technique, and unanswered questions remain regarding its acute and chronic impact on neural excitability and various aspects of brain function. Recent work with TMS has demonstrated its unique role in complementing other tools (e.g. fMRI, PET and high-resolution EEG) for studying brain function. As a brain intervention tool, TMS holds the promise of moving beyong correlative studies to help define the functional role of cortical regions in selected cognitive and affective processes. In addition to providing indices of cortical excitability, these methods allow one to study brain connectivity directly. On the other hand, the combination of TMS and high-resolution EEG may often be the method of choice for basic neurosciencee and for clinical diagnosis, e.g. in the assessment of brain connectivity in patients suffering from neurodegenerative diseases.
Descriptors		MOTOR CORTEX ELECTROMAGNETIC FIELDS ELECTROMYOGRAPHY SAFETY