Author/Editor		Pavšelj, N; Pavlin, M; Miklavčič, D
Title		Dependency of induced transmembrane potential on the cells inside a cell cluster
Type		članek
Source		Medicon 2001. 9th Mediterranean conference on medical and biological engineering and computing. 2nd Croatian-Slovenian meeting on biomedical engineering. 1st international conference on muscle fibre structure and function. 5th symposium of Croatian society for medical informatics (Medicine informatics 2001). Proccedings of the International federation for medical and biological engineering. Part 1, Part 2; 2001 Jun 12-15; Pula
Publication year		2001
Volume		str. 828-31
Language		eng
Abstract		To study electroporation of cell clusters as models of tumors, we studied how the transmembrane potential on cells inside the cluster is dependent on the cell position inside the cluster. Namely, in biological tissues cells are always surrounded by other cells, which modify external electric field. We used numerical analysis performed by commercial finite element modelling software. We established that there is no radial dependence of induced transmembrane potential of the cells inside the cluster. We also demonstrated that transmembrane potential of the cells inside the cluster does not depend on the size of the cluster. However, we noticed small differences on the border of a cluster. These differences are due to the fact that clusters deviate from spherical shape, which alters electric field on the border of a cluster.
Descriptors		ELECTROPORATION MEMBRANE POTENTIALS NEOPLASMS MODELS, THEORETICAL