Avtor/Urednik     Strle, Franc
Naslov     Okužbe z bakterijo Chlamydia pneumoniae in ateroskleroza
Prevedeni naslov     Infections with Chlamydia pneumoniae and atherosclerosis
Tip     članek
Vir     In: Reberšek-Gorišek J, Baklan Z, Kotnik-Kevorkijan B, editors. Zbornik predavanj in praktikum Bedjaničev simpozij z mednarodno udeležbo o temi klamidijske okužbe; 2001 jun 8-9; Maribor. Maribor: Splošna bolnišnica Maribor,
Leto izdaje     2001
Obseg     str. 143-54
Jezik     slo
Abstrakt     Data on the association between atherosclerosis and infection with Chlamydia pneumoniae are presented in a review article. The association has been suggested by the findings of several epidemiological and seroepidemiological studies, supported by the presence of C. pneumoniae in atherosclerotic vessel lesions and by the findings of in vitro studies, and demonstrated in animal studies by the induction of (atherosclerotic) inflammatory changes and/or enhancement of the influence of traditional atherosclerosis risk factors on the course of atherosclerosis, as well as by prevention of the lesions by early antibiotic treatment. Several clinical studies on the influence of antibiotic treatment on the course of coronary artery disease are in progress. While there is no doubt about the association between atherosclerosis and C. pneumoniae infection, the eventual etiologic role of this infection remains to be established. l. pneumoniae infections might have been the etiologic agent of atherosclerosis, one of the risk factors or just an innocent bystander of atherosclerosis; the last possibility seems to be rather remote. There have been no reliable reasons for routine treatment of coronary heart disease with antibiotics in everyday clinical practice.
Deskriptorji     ATHEROSCLEROSIS
CHLAMYDIA PNEUMONIAE
ANTIBIOTICS