Avtor/Urednik | Pauluzzi, P | |
Naslov | Therapy of Lyme borreliosis | |
Tip | članek | |
Vir | Acta Dermatovenerol Alp Pannon Adriat | |
Vol. in št. | Letnik 10, št. 4 | |
Leto izdaje | 2001 | |
Obseg | str. 159-61 | |
Jezik | eng | |
Abstrakt | Despite many studies that have been carried out recently, there is still no standard treatment for Lyme borreliosis. The factors that must be taken into consideration in treating the disease are the intrinsic sensitivity of the pathogen Borrelia burgdorferi, tissue penetration of the antibiotic, the characteristics of the pathogen, such as long generation time (7-20 h), intracellular localization, persistence in tissues with a poor blood supply (e.g. synovia), penetration of the blood-brain barrier, and varying antibiotic resistance of different pathogen strains. A generally accepted antibiotic treatment regimen has yet to be established, and all treatment recommendations are essentially provisional. | |
Deskriptorji | LYME DISEASE BORRELIA BURGDORFERI |