Author/Editor		Glaser, Marjana
Title		Pojav trombotične trombocitopenične purpure pri bolniku s karcinomom
Translated title		Thrombotic thrombocytopenic purpura in patients suffering of cancer
Type		članek
Source		Zdrav Vestn
Vol. and No.		Letnik 71, št. 7-8
Publication year		2002
Volume		str. 433-5
Language		slo
Abstract		Background. Thrombotic thrombocytopenic purpura (TTP) is a rare group of symptoms, characterized by microangiopathic haemolytic anemia, thrombocytopenia, neurological symptoms, fever and renal affection. Beside other causes, TTP is a rare symptom in cancer. TTP must be treated immediately and it is necessary to search for its cause. Patients. In the article two patients with acute TTP are represented. When searching for the reason of TTP, in first patient gastric carcinoma and in second patient peritoneal carcinosis and later breast carcinoma were established. Before surgical treatment, both patients were treated with repeated plasmapheresis. Conclusions. Treatment of acute from of TTP in cancer patients is the same as in other diseases, especially to softening the symptoms and to make possible the surgical treatment. Further course of TTP depends on disease extension.
Summary		Izhodišča. Trombotična trombocitopenična purpura (TTP) je skupek bolezenskih znakov, za katere so značilni mikroangiopatična hemolitična anemija, trombocitopenija, nevrološki znaki, zvišana telesna temperatura in prizadetost ledvic. Redko opazujemo pojav TTP pri karcinomih. TTP je potrebno začeti zdraviti takoj in poiskati njen vzrok. Bolniki. V sestavku sta predstavljeni dve bolnici, ki sta zboleli z akutno obliko TTP. Pri iskanju vzroka bolezni smo pri prvi bolnici ugotovili želodčnega raka, pri drugi pa karcinozo peritoneja in kasneje raka na obeh dojkah. Pred operativnim posegom smo ju zdravili s plazmaferezami. Zaključki. Akutno TTP pri karcinomu zdravimo enako kot pri drugih vzrokih predvsem zato, da zmanjšamo težave in pripravimo bolnika na operativni poseg. Nadaljni potek je odvisen od razširjenosti karcinoma in uspešnosti operativnega posega.
Descriptors		PURPURA, THROMBOTIC THROMBOCYTOPENIC STOMACH NEOPLASMS BREAST NEOPLASMS MIDDLE AGE