Avtor/Urednik     Benoit, Evelyne; Mattei, Cesar; Ouanounou, Gilles; Meunier, Frederic A; Šuput, Dušan; Le Gall, Frederic; Marquais, Michel; Dechraoui, Marie Y; Molgo, Jordi
Naslov     Ionic mechanisms involved in the nodal swelling of myelinated axons caused by marine toxins
Tip     članek
Vir     Cell Mol Biol Lett
Vol. in št.     Letnik 7, št. 2
Leto izdaje     2002
Obseg     str. 317-21
Jezik     eng
Abstrakt     This review describes the ionic mechanisms involved in the nodal swelling of frog myelinated axons caused by specific marine neurotoxins (ciguatoxins, brevetoxins, Conus consors toxin and equinatoxin-II), analysed using confocal laser scanning microscopy. We have focussed on toxins that either target neuronal voltage-dependent Na+ channels, or that form cationselective pores and indirectly affect the functioning of the Na+-Ca++ exchanger.
Deskriptorji     AXONS
CIGUATOXIN
CNIDARIAN VENOMS
MARINE TOXINS
NEUROTOXINS
CATIONS
RANVIER'S NODES
SODIUM CHANNELS
RANIDAE