Avtor/Urednik		Špiclin, Polona; Gašperlin, Mirjana
Naslov		Vitamin C in koža
Prevedeni naslov		Vitamin C and the skin
Tip		članek
Vir		Farm Vestn
Vol. in št.		Letnik 52, št. 4
Leto izdaje		2001
Obseg		str. 287-93
Jezik		slo
Abstrakt		Vitamin C has been used in cosmetic and pharmaceutical skin care products since it has many favorable effects on the skin. As an antioxidant agent, vitamin C can scavenge and destroy reactive oxidizing agents and other free radicals. Because of this capability it represents an important protection against UV induced damage. Vitamin C also improves the elasticity of the skin and reduces wrinkles by stimulating the synthesis of collagen. By suppressing the pigmentation the drug influences the complexion of the skin. The use of vitamin C in products is limited due to its low stability. It is more convenient to use vitamin C derivatives, for example ascorbyl palmitate and ascorbyl phosphate salts. Both derivatives demonstrate an improved chemical stability, but differ in hydro-lipophilic behaviour, which determines the ability of the drug to permeate the skin.
Izvleček		Vitamin C ima na koži mnogo ugodnih učinkov, zato se v zadnjem času pogosto pojavlja v kozmetičnih in farmacevtskih izdelkih za kožo. Kot antioksidant odstranjuje reaktivne kisikove spojine in druge proste radikale, zato predstavlja pomemben del zaščite kože pred UV sevanjem. Poleg tega vitamin C s stimulacijo sinteze kolagena izboljša elastičnost kože in zmanjša nastajanje gub, z zaviranjem pigmentacije pa vpliva na obarvanost kože. Vitamin C je za vgrajevanje v izdelke neprimeren, ker je zelo nestabilen. Smiselna je uporaba derivatov vitamina C, npr. askorbil palmitata ali soli askorbil fosfatov. Oba derivata imata izboljšano kemijsko stabilnost, razlikujeta pa se v hidro-lipofilnih lastnostih, ki določajo sposobnost prehajanja v kožo.
Deskriptorji		ASCORBIC ACID SKIN SKIN CARE SKIN AGING ANTIOXIDANTS COLLAGEN SKIN PIGMENTATION