| Author/Editor | Štrumbelj, Iztok; Seme, Katja | |
| Title | Batahemolitični streptokoki skupin B in G iz Pomurja - značilnosti izolatov, odpornih proti antibiotikom | |
| Translated title | Group B and G beta-hemolytic streptococci in Pomurje region - characteristics of antimicrobial resistant isolates | |
| Type | članek | |
| Source | Zdrav Vestn | |
| Vol. and No. | Letnik 72, št. 5 | |
| Publication year | 2003 | |
| Volume | str. 283-6 | |
| Language | slo | |
| Abstract | Background. Macrolide-resistant strains of betahemolytic streptococci have been isolated in Pomurje region in Slovenia. The aim of the study was to determine phenotypes of macrolide-lincozamide resistance and patterns of resistance to selected antibiotics in these isolates. Methods. Twenty-one erythromycin-resistant isolates from group B and group G beta-hemolytic streptococci, obtained from patients in Pomurje were analyzed. Phenotypes of macrolide-lincozamide resistance were determined in all isolates. In group B and group G streptococci susceptibility to 8 and 14 antibiotics was tested, respectively. Results. All 42 isolates were susceptible to penicillin and vancomycin. The majority of erythromycin-resistant group B streptococci isolates was tetracycline-resistant but susceptible to chloramphenicoland of loxacin. In erythromycin-resistant isalates of group G streptococci 5 different resistance patterns were found. The most frequent pattern was a resistance to multiple antibiotics (besides erythromycin also to midekamycin, clindamycin, tetracycline, chloramphenicol and several fluoroquinolones). Conclusions. These resistant isolates are unique and represent novel example of a strong bacterial ability to adapt to changes in their environment and consequently survive in the presence of antibiotics. | |
| Summary | Izhodišča. V Pomurju smo osamili proti makrolidom odporne seve betahemolitičnih streptokokov. Želeli smo preučiti fenotipe te odpornosti in občutljivost za izbrane antibiotike drugih skupin. Metode. Analizirali smo po 21 proti eritromicinu odpornih izolatov betahemolitičnih streptokokov skupin B in G, ki so bili osamljeni pri bolnikih v Pomurju. Pri vseh izolatih smo določili fenotipe makrolidno-linkozamidne odpornosti in občutljivost za 8 antibiotikov pri skupini B in 14 antibiotikov pri skupini G. Rezultati. Vseh 42 izolatov je bilo občutljivih za penicilin in vankomicin. Streptokoki skupine B so bili večinoma odporni proti tetraciklinu, a občutljivi za kloramfenikol in ofloksacin. Pri izolatih skupine G smo našli 5 vzorcev odpornosti proti testiranim antibiotikom, najpogostejši vzorec odpornosti je bila hkratna odpornost izolatov proti številnim antibiotikom (eritromicinu, midekamicinu, klindamicinu, tetraciklinu, kloramfenikolu in različnim fluorokinolonom). Zaključki. Preučevani izolati so izjemni v svetovnem merilu in so nov zaskrbljujoči primer izredne prilagodljivosti bakterij in njihove posledične sposobnosti preživetja v prisotnosti antibiotikov. | |
| Descriptors | STREPTOCOCCUS STREPTOCOCCUS AGALACTIAE DRUG RESISTANCE, MICROBIAL ANTIBIOTICS, MACROLIDE ERYTHROMYCIN CHLORAMPHENICOL RESISTANCE CLINDAMYCIN OFLOXACIN TETRACYCLINE RESISTANCE PENICILLIN RESISTANCE LATEX FIXATION TESTS |