Avtor/Urednik		Bensadon, M; O'Quigley, J
Naslov		Integral evaluation for continual reassessment method
Tip		članek
Vir		Comput Methods Programs Biomed
Vol. in št.		Letnik 42, št. 4
Leto izdaje		1994
Obseg		str. 271-3
Jezik		eng
Abstrakt		In this paper we show how the exact analytical solutions to the numerical integrals required in the implementation of the continual reassessment method can be evaluated. The formulas have been given but, with increasing sample size, rapidly become unwieldy. We develop an algorithm which uses the numerical binary representation of the subset size and, in the process, enables us to easily identify those members of the subset needed in the integral evaluation. The complex combinatorial problem of selecting the set of all subsets with a particular characteristic is then greatly simplified. We describe the nature and type of all the variables and parameters used in a PASCAL procedure.
Deskriptorji		MATHEMATICAL COMPUTING ALGORITHMS