Author/Editor		Rudolf, Z
Title		Novosti v kemoterapiji raka
Translated title		Advances in cancer chemotherapy
Type		članek
Source		Med Razgl
Vol. and No.		Letnik 30, št. 2
Publication year		1991
Volume		str. 217-29
Language		slo
Abstract		The hitherto development of systemic treatment - cancer chemotherapy is presented and analysed. The main approaches to chemotherapy, such as induction chemotherapy, adjuvant chemotherapy, primary chemotherapy and individually planned chemotherapy, are discussed. The principal problems associated with present cancer chemotherapy include resistance of cancer cells to anticancer drugs and toxic effects of these drugs on healthy tissue, which requires dose reduction. The methods used to enhance the effectiveness and reduce toxicity of chemotherapy are presented together with some new aspects of systemic therapy. The available methods of targeted drug therapy and, in perspective, genetic treatment and
Descriptors		NEOPLASMS ANTINEOPLASTIC AGENTS BIOLOGICAL RESPONSE MODIFIERS NEOPLASM STAGING DRUG RESISTANCE DOSE-RESPONSE RELATIONSHIP, DRUG