Avtor/Urednik		Marko, PB; Rejc-Marko, J
Naslov		Diferencialna diagnoza medikamentoznih eksantemov
Prevedeni naslov		Differential diagnosis of cutaneous drug reactions
Tip		članek
Vir		In: Miljković J, Berčič M, Marko PB, editors. Zbornik predavanj Dermatološki dnevi: strokovno izpopolnjevanje iz dermatologije z mednarodno udeležbo; 2003 nov 7-8; Maribor. Maribor: Splošna bolnišnica,
Leto izdaje		2003
Obseg		str. 101-12
Jezik		slo
Abstrakt		Cutaneous reactions are among the most trequenuy ooservea reacnons to drugs. The majority of reactions are mild, accompanied by pruritus, resolving promptly after the offending drug is discontinued. Severe, lifethreatening cutaneous drug reactions (CDRs) do occur and are unpredictible. Prompt identification of CDRs. withdrawal of the offending agent and therapeutic intervention may help to limit the total toxicity associated with the drug. Drug eruptions can mimic virtually all the morphologic expresions in dermatology and should be considered in the differential diagnosis of any symmetric cutaneous eruption with sudden onset in a patient who takes medications. Careful history. laboratory and histologic findings may help in differential diagnostic workup to establish a diagnosis of CDRs. Rechallenge with the offending drug would in most cases give definitive proof. In the article, the most common CDRs and their principal differential diagnostic considerations are described.
Deskriptorji		DRUG ERUPTIONS DIAGNOSIS, DIFFERENTIAL VIRUS DISEASES URTICARIA ANGIONEUROTIC EDEMA ERYTHEMA MULTIFORME EPIDERMAL NECROLYSIS, TOXIC LICHENOID ERUPTIONS ERYTHEMA NODOSUM VASCULITIS