Avtor/Urednik		Anderluh, Gregor; Maček, Peter; Lakey, Jeremy H
Naslov		Peeking into a secret world of pore-forming toxins: membrane binding processes studied by surface plasmon resonance
Tip		članek
Vir		Toxicon
Vol. in št.		Letnik 42
Leto izdaje		2003
Obseg		str. 225-8
Jezik		eng
Abstrakt		Pore-formation in cell membranes is used by many toxins to kill cells. It is usually a process involving multiple steps that are difficult to analyse at the molecular level. The use of surface plasmon resonance (SPR) has only recently been introduced into the study of pore-forming toxins (PFT). It can give useful data mostly on the first steps of the pore-forming process; the binding to the lipid membranes. In particular, it can make unique contributions to our knowledge of ligand specificity and the kinetics of binding. This mini-review summarizes some recent SPR studies of PFT.
Deskriptorji		CNIDARIAN VENOMS LIPID BILAYERS CELL MEMBRANE PERMEABILITY BINDING SITES PROTEIN BINDING SEA ANEMONES MOLECULAR PROBE TECHNIQUES