Avtor/Urednik		Koritnik, Blaž
Naslov		Funkcijsko magnetnoresonančno slikanje motoričnih področij možganov med hotenimi gibi pri desničnih in levičnih osebah
Tip		monografija
Kraj izdaje		Ljubljana
Založnik		Medicinska fakulteta
Leto izdaje		2003
Obseg		str. 43
Jezik		slo
Abstrakt		The goal of functional neuroimaging is to measure and map the activity of the brain in space and time. Functional magnetic resonance imaging (fMRI) is used to show which brain areas are active during certain tasks. It is based on local changes of haemoglobin concentration due to cortical neural activity. Because of a good spatial resolution, non-invasiveness and availability, fMRI is a suitable method for the study of brain motor areas. Cortical motor areas and cerebellum are involved in planning and execution of voluntary movements. There are at least four cortical motor areas: primary motor cortex, lateral premotor cortex, supplementary motor area, and cingulate motor area. They have different functions, microstructure, and connectivity. Motor areas show structural and functional asymmetry. Brain activation patterns during voluntary finger movements are influenced by rate, force, amplitude, and complexity of movements. Two other factors are handedness and hand involvement. In our study, we have aimed to measure the effect of movement rate and handedness on the extent and laterality of motor areas activation during finger movements. We have used a handedness inventory and hand performance tests to assess the degree of handedness in two groups of right- and left-handed healthy subjects. The activation of brain motor areas was measured by fMRI during right- and left-hand finger tapping at two different rates. A GE 1,5 T scanner was used for EPI images acquisition (16 axial slices every 3 s). A general linear model based statistical analysis was used to measure the extent and laterality of activation in cortical and cerebellar regions of interest. The extent of activation was greater during fast movements in all motor areas except for the contralateral lateral sensorimotor area; the cortical and cerebellar activation was less lateralized. (Abstract truncated at 2000 characters).
Deskriptorji		MOTOR CORTEX MAGNETIC RESONANCE IMAGING MOVEMENT FINGERS LATERALITY MOTOR SKILLS