Avtor/Urednik		Benedik, Janez
Naslov		Vpliv tramadola na zdravljenje pooperativne bolečine po odstranitvi žrelnice in nebnic pri otrocih
Tip		monografija
Kraj izdaje		Ljubljana
Založnik		Medicinska fakulteta
Leto izdaje		2003
Obseg		str. 46
Jezik		slo
Abstrakt		Tonsillectomy with adenoidectomy is one of the most commonly performed surgical procedures during childhood. Nausea and vomiting together with inadequate postoperative analgesia increase restlessness of the child and incidental postoperative bleeding. Tramadol, a centraly acting analgesic with low affinity for opioid receptors, could be an effecive alternative for the relief of postoperative pain in children. In a randomized prospective study a comparison of postoperative analgesia, after tonsillectomy with adenoidectomy in children, provided with acetaminophen or tramadol was done. Our hypothesis stated that, tramadol received intravenously after induction of general anaesthesia has superior analgesic effect compared to acetaminophen. We studied 108 children (3-7 years) scheduled for tonsillectomy with adenoidectomy. Half of children received tramadol 2 mg/kg of body weight i.v. before surgical incision (tramadol group), while the second group received acetaminophen elixir 15 mg/kg of body weight (acetaminophen group). For postoperative analgesia, each child received acetaminophen suppositories (10 mg/kg of body weight) on four to six hours. Rescue medication consisted of combined suppositories. A standard anaesthetic technique was used; each child received propofol, alfentanil and vecuronium for endotracheal intubation. Anaesthesia was maintained with propofol and 60% nitrous oxide in oxygen with intermittent positive pressure ventilation of the lungs. At the end of surgery, all anesthetics were discontinued, and extubation was performed when spontaneous breathing was regarded as adequate. Residual neuromuscular blockade was antagonized with neostigmine and atropine. At induction of anaesthesia, during surgery and awakening from anaesthesia all specialities were recorded. (Abstract truncated at 2000 characters).
Deskriptorji		PAIN, POSTOPERATIVE TRAMADOL TONSILLECTOMY ADENOIDECTOMY ACETAMINOPHEN CHILD PAIN MEASUREMENT OXIMETRY POSTOPERATIVE COMPLICATIONS NAUSEA VOMITING PROSPECTIVE STUDIES