Avtor/Urednik		Mrvič, Tatjana; Marin, Jožica
Naslov		Okužbe z metapnevmovirusom
Prevedeni naslov		Infections with metapneumovirus
Tip		članek
Vir		Med Razgl
Vol. in št.		Letnik 43, št. Suppl 2
Leto izdaje		2004
Obseg		str. 131-4
Jezik		slo
Abstrakt		Human metapneumovirus (hMPV) is a newly discovered respiratory pathogen related with infections in children and adults. Serological studies have showed that by the age of five years virtualy all children have been exposed to that virus. Infections can be asimptomatic. The clinical simptoms are similar to those caused by respiratory syncytial virus. In small children most infections appear as acute bronchiolitis or pneumonia, and in adult patients it is almost impossible to distinguish them from infections caused by other respiratory viruses. RT-PCR (reverse transcription - polymerase chain reaction) is the method used for detection of the virus. Since the virus has been identified only three yaears ago, its clinical and economical importance has yet to be determinated.
Izvleček		Človeški metapnevmovirus (hMPV) je novoodkriti patogen dihalnih poti, ki ga povezujejo z okužbami dihal pri otrocih in odraslih. Do petega leta starosti skoraj vsi otroci v serumu razvijejo protitelesa proti omenjenemu virusu. Okužbe lahko potekajo brezsimptomno ali pa s klinično sliko, ki najbolj spominja na okužbe z respiratornim sincicijskim virusom (RSV). Pri majhnih otrocih se okužba kaže kot akutni bronhiolitis ali pljučnica, pri odraslih bolnikih pa jo je klinično nemogoče ločiti od okužb z drugimi virusi dihal. V diagnostične namene za dokazovanje virusa se trenutno uporablja metoda RT-PCR (reakcija s hMPV reverzno transkripcijo in polimerazno verižno reakcijo). Ker je bil virus odkrit šele pred tremi leti, klinični in ekonomski pomen okužb s hMPV zaenkrat še ni pojasnjen.
Deskriptorji		PARAMYXOVIRIDAE RESPIRATORY TRACT INFECTIONS PARAMYXOVIRUS INFECTIONS