Avtor/Urednik		Kersnik-Levart, Tanja
Naslov		Občutljivost ultrazvočne preiskave ledvic za ugotavljanje sprememb ledvičnega parenhima pri otrocih
Prevedeni naslov		Sensitivity of ultrasonography in detecting renal parenchymal defects in children
Tip		monografija
Kraj izdaje		Ljubljana
Založnik		Univerza v Ljubljani, Medicinska fakulteta
Leto izdaje		2004
Obseg		str. 43
Jezik		slo
Abstrakt		2. 1. BACKGROUND Renal parenchimal defects (RPD) - renal scars, hypoplasia/dysplasia in children are a major risk factor for chronic renal failure. In general it is accepted that children after urinary tract infection should undergo diagnostic evaluation and that those found to have RPD should be followed for many years. Many clinical trials that compared dimercaptosuccinic acid renal scan (DMSA) and ultrasonography (US) in RPD detection, have shown a better sensitivity of DMSA but unfortunately it posses quite a radiation hazard to the patient. Most authors would agree that RPD should be detected and followed by DMSA, as US does not seem to be sensitive enough for this purpose. However, clinical observation show that it might well be the other way around, namely, that DMSA is too sensitive and detects RPD that are too small to be clinically significant. 2. 2. PURPOSE OF THE STUDY The purpose of this study is to evaluate the sensitivity of US in identifying patients with clinically significant RPD and in detecting RPD of various grades as seen by DMSA. 2. 3. PATIENTS AND METHODS In 89 children with abnormal DMSA, a second DMSA, US, and other tests for evaluating renal function were performed at least one year after the first DMSA. The extent of RPD detected by DMSA and US was correlated with renal function parameters. 2.4. RESULTS In all five patients with diminished renal function, RPD were detected by both DMSA and US. In addition, US was able to detect clinically insignificant RPD in 48 out of 67 cases (71,6%). 2.5. CONCLUSIONS The present study has shown that, compared to DMSA, US seems to be sensitive enough to detect clinically significant RPD in children. The substitution of DMSA with US would be beneficial, as this would eliminate radiation exposure, reduce costs and increase availability.
Deskriptorji		URINARY TRACT INFECTIONS KIDNEY DISEASES SUCCIMER SENSITIVITY AND SPECIFICITY CHILD