Avtor/Urednik		Pečovnik-Balon, Breda
Naslov		Periferna arterijska bolezen in ledvice
Prevedeni naslov		Peripheral artery disease and the kidney
Tip		članek
Vir		Med Razgl
Vol. in št.		Letnik 43, št. Suppl 1
Leto izdaje		2004
Obseg		str. 115-7
Jezik		slo
Abstrakt		Peripheral artery disease (PAD) is associated with increased morbidity and mortality rates in patients with chronic renal failure (CRF). Among patients with CRF, the prevalence of PAD is higher than in the remaining population of corresponding age. The cause is accelerated atherosclerosis, presumably produced by non-standard factors associated with CRF. These include chronic inflammation, increased lipoprotein (a) and homocysteine levels, and calcifications of the arterial wall. The diagnostic methods used in the remaining population are not always applicable to patients with CRF, as they are inaccurate due to vascular calcifications. The preventative measures are the same as for the rest of the population, while the therapeutic measures remain problematic since revascularization as well as amputation are poorly tolerated by CRF patients.
Izvleček		Periferna arterijska bolezen (PAB) je povezana s povečano obolevnostjo in smrtnostjo pri bolnikih s kronično ledvično odpovedjo (KLO). Prevalenca PAB med bolniki s KLO je večja kot pri ostali primerljivo stari populaciji. Vzrok je pospešena ateroskleroza, za katero so najverjetneje krivi neklasični dejavniki, povezani s KLO. To so kronično vnetje, zvišana raven lipoproteina (a), homocisteina in kalcifikacije arterijske stene. Diagnostične metode, ki se uporabljajo pri ostali populaciji, niso vedno prenosljive na bolnike s KLO, ker so nenatančne zaradi žilnih kalcifikacij. Preventivni ukrepi so enaki kot pri ostali populaciji, terapevtski ukrepi pa ostajajo problematični, ker bolniki s KLO slabo prenašajo revaskularizacijo in amputacijo.
Deskriptorji		PERIPHERAL VASCULAR DISEASES ARTERIAL OCCLUSIVE DISEASES KIDNEY FAILURE, CHRONIC RISK FACTORS