Avtor/Urednik     Lopuh, Mateja
Naslov     Vpliv torakalne epiduralne analgezije na dihalno funkcijo po pljučnih operacijah: primerjava ropivakaina z mešanico bupivakaina, morfina in klonidina
Tip     monografija
Kraj izdaje     Ljubljana
Založnik     Medicinska fakulteta
Leto izdaje     2004
Obseg     str. 67
Jezik     slo
Abstrakt     Introduction Analgesic efficacy of 0.2% ropivacaine for pain treatment after lung surgery has been evaluated, using patient controlled epidural analgesia (PCEA). Lung function after surgery has been assessed by spirometric measurements of forced expiratory volume in first second (FEV,) and forced vital capacity (FVC) and measurements of maximal inspiratory (MIP) and expiratory pressures (MEP) and results were compared between the two groups of patients, receiving 0.2% ropivacaine and a mixture of bupivacaine, morphine and clonidine. Side effects of morphine and piritramide were compared between groups. Methods 37 patients, ASA II and III with lung cancer, undergoing lobectomy, were included in a prospective, randomized, double blind study after obtaining their written informed consent. On a day before the planned surgery, the patients performed baseline measurements of FEV,, FVC, MlP and MEP. Patients were randomly assigned to two groups. In group A 0.2% ropivacaine in 100 ml of saline was used for postoperative pain treatment by PCEA and in group 8 a mixture of 10 mg morphine, 50 mg bupivacaine in 0.15 mg clonidine in 100 ml of saline. Epidural cathefer was inserted at the T6-7 or T7-8 level and its position was confirmed by 4 ml of 2% lidocaine. After that a preemptive dose of 4 mg morphine was injected through the catheter. Both groups of patients underwent surgery under same general anaesthesia. (Abstract truncated at 2000 characters)
Deskriptorji     PAIN, POSTOPERATIVE
ANALGESIA, EPIDURAL
BUPIVACAINE
CLONIDINE
MORPHINE
SPIROMETRY
FORCED EXPIRATORY VOLUME
VITAL CAPACITY
LUNG NEOPLASMS
OXIMETRY
BLOOD PRESSURE
CENTRAL VENOUS PRESSURE
PAIN MEASUREMENT