Avtor/Urednik		Crnjac, Anton; Sok, Mihael; Kamenik, Mirt; Antonič, Jože; Zorko, Anton; Veingerl, Bojan; Vidovič, Damjan
Naslov		pH vrednost malignega plevralnega izliva raka dojke kot napovedni dejavnik uspešnosti plevrodeze
Prevedeni naslov		Malignant pleural effusion pH in patients with breast carcinoma as a predictability factor on the efficacy of pleurodesis
Tip		članek
Vir		In: Crnjac A, editor. Zbornik predavanj Strokovni simpozij z mednarodno udeležbo ob 50-letnici Oddelka za torakalno kirurgijo; 2004 nov 19; Maribor. Maribor: Splošna bolnišnica Maribor,
Leto izdaje		2004
Obseg		str. 67-76
Jezik		slo
Abstrakt		Objective: A prospective randomised study was conducted to compare the efficacy of treating malignant pleural effusions (MPE) in patients with breast carcinoma by thoracoscopic mechanical pleurodesis (TMP) as a new palliative treatment and talc pleurodesis (TP) at various pleural fluid pH levels and to determine whether at low pH values, when the success of TP is reduced, TMP is more successful. Methods: 87 female patients with breast carcinoma and a resulting MPE resistant to systemic therapy were divided into two groups. In group 1 TMP, 24 patients with pH levels above 7.3 and 21 patients with pH levels below 7.3 underwent thoracoscopic parietal and visceral pleural abrasion utilising general anaesthesia. In group 11 TP, 22 patients with pH levels above 7.3 and 20 patients with pH levels below 7.3 were administered 5 g of sterile talc, dissolved in 100 ml of physiological solution, via a chest tube, utilising local anaesthesia. Postoperative follow-up was performed to determine a possible recurrence of MPE with periodic radiographs, the duration of chest tube drainage and hospitalisation, occurrence of complications, and perioperative mortality The following was used for statistical analysis: t-test for odd samples, [f test, logistic regression, and multiple linear regression. Results: TMP and TP were equally successful (92% and 91%) in patients with pH levels above 7.3. Differences occurred in patients with pH below 7.3 (81% and 55%) (p=0.07). The lowest pH value at which TMP proved successful was 7.06, while for TP this value was 7.25. In TMP group the average duration of chest tube drainage amounted to 3.8 days and hospitalisation to 5.5 days, while in TP group it was 5.6 days and 7.5 days, respectively. Differences were statistically significant (p<0.05). (Abstract truncated at 2000 characters).
Deskriptorji		BREAST NEOPLASMS PLEURAL EFFUSION, MALIGNANT THORACOSCOPY PLEURODESIS HYDROGEN-ION CONCENTRATION TALC AGE FACTORS PROGNOSIS TREATMENT OUTCOME