Avtor/Urednik		Mlačak, Blaž; Rotar-Pavlič, Danica; Ivka, Branimir; Krajačič, Boris
Naslov		Periferna arterijska okluzivna bolezen in krčne žile pri diabetikih
Prevedeni naslov		Peripheral arterial occlusive disease and varicose veins in diabetic patients
Tip		članek
Vir		Zdrav Vestn
Vol. in št.		Letnik 73, št. 12
Leto izdaje		2004
Obseg		str. 885-7
Jezik		slo
Abstrakt		Background. Diabetes mellitus is an independent risk factor which increase cardiovascular morbidity and mortality by 1.5-3 times. The aim of this study was to determine the difference in the frequency of peripheral arterial occlusive disease, mediacalcinosis of the lower limbs and varicose veins between diabetic patients and healthy subjects. Patients and methods. The test group included 138 diabetic patients, 60 males and 78 females, aged between 23 and 88. The control group consisted of 138 patients without diabetes, who were comparable to the test group by age, sex, and profession. Peripheral arterial occlusive disease and mediacalcinosis were diagnosed in the lower extremities by means Doppler ultrasound and electronic oscillography. Varicose veins were diagnosed clinicaly. Results. Peripheral arterial occlusive disease was diagnosed in 26% of patients with diabetes mellitus, and in 8.7% of the control group. The difference is statistically significant (p < 0.001). Mediacalcinosis of the lower limbs was diagnosed with 8.7% of the diabetic patients and 3.6% of healthy controls (p < 0.05). 70.3% patients in the diabetic group and 68% patients in the control group had varicose veins of the lower limbs. This difference is not statistically significant, as the differences did not appear at all stages of chronic venous insufficiency. Conclusions. Our study has demonstrated that peripheral arterial occlusive disease is frequently present in diabetes mellitus. We are certainly justified in determining the presence of other risk factors in diabetes with the aim of early prevention and therapy.
Izvleček		Izhodišča. Sladkorna bolezen je samostojen dejavnik tveganja za aterosklerozo, ki za 1,5- do 3-krat povečuje incidenco srčno žilnih zapletov. Cilj naše raziskave je bil ugotoviti razliko v pogostosti periferne arterijske okluzivne bolezni, mediokalcinoze na spodnjih udih in krčnih žil med diabetiki in zdravimi preiskovanci. Metode. V testni skupini je bilo 138 diabetikov med 23. in 88. letom starosti, od tega 60 moških in 68 žensk. Kontrolna skupina, ki je imela 138 preiskovancev brez diabetesa, je bila primerljiva s testno po starosti, spolu in poklicu. Periferno arterijsko okluzivno bolezen in mediokalcinozo na spodnjih udih smo diagnosticirali s pomočjo ultrazvočnega doplerskega detektorja in elektronskega oscilografa, medtem ko smo krčne žile ugotavljali s kliničnim pregledom. Rezultati. Periferno arterijsko okluzivno bolezen smo diagnosticirali pri 26% diabetikov in pri 8,7% preiskovancih kontrolne skupine. Razlika je statistično pomembna (p < 0,001). Mediokalcinozo na arterijah spodnjih udov smo ugotovili pri 8,7% diabetikov in pri 3,6% preiskovancih kontrolne skupine (p < 0,05). 70,3% diabetikov in 68% preiskovancev kontrolne skupine je imelo krčne žile na spodnjih udih. Razlika v prevalenci krčnih žil in kroničnega venskega popuščanja med testno in kontrolno skupino ni bila statistično pomembna. Zaključki. Raziskava je pokazala, da je periferna arterijska okluzivna bolezen pogosta pri preiskovancih z diabetesom. Ugotavljanje dejavnikov tveganja za aterosklerozo in zgod nja diagnoza periferne arterijske okluzivne bolezni pri diabetikih sta upravičena s ciljem preprečevanja aterosklerotičnih zapletov.
Deskriptorji		DIABETES MELLITUS ARTERIAL OCCLUSIVE DISEASES VARICOSE VEINS