Avtor/Urednik		Lotrič-Furlan, Stanka; Petrovec, Miroslav; Avšič-Županc, Tatjana; Strle, Franc
Naslov		Comparison of patients fulfilling criteria for confirmed and probable human granulocytic ehrlichiosis
Tip		članek
Vir		Scand J Infect Dis
Vol. in št.		Letnik 36
Leto izdaje		2004
Obseg		str. 817-22
Jezik		eng
Abstrakt		In order to assess the validity of definitions for human granulocytic ehrlichiosis (HGE), epidemiological, clinical and laboratory findings for 13 patients with confirmed HGE and 21 patients fulfilling criteria for probable HGE were compared. The patients were identified during a prospective study on the aetiology of febrile illness occurring after a tick bite, performed in Slovenia from 1995 to 2002. Significant differences between the 2 groups were found for age of patients, duration of fever before the first examination, and several clinical and laboratory parameters including the occurrence of chills, myalgia, arthralgia, leukopenia, thrombocytopenia, abnormal liver function tests results, and elevated concentration of C-reactive protein. All the abnormalities were established more often in patients with confirmed HGE than in those with probable HGE. Patients with confirmed HGE exhibited higher geometric mean titre values and higher peak antibody titres to Anaplasma phagocytophilum that developed later in the course of their illness. The differences indicate that in some patients fulfilling criteria for probable HGE the signs and symptoms most probably are not the result of a recent infection with A. phagocytophilum.
Deskriptorji		EHRLICHIOSIS C-REACTIVE PROTEIN ASPARTATE AMINOTRANSFERASE ALANINE AMINOTRANSFERASE IGG LACTATE DEHYDROGENASE CREATINE KINASE POLYMERASE CHAIN REACTION