Avtor/Urednik		Hristovski, Dimitar; Peterlin, Borut; Mitchell, Joyce A; Humphrey, Susanne M
Naslov		Using literature-based discovery to identify disease candidate genes
Tip		članek
Vir		Int J Med Inf
Vol. in št.		Letnik 74
Leto izdaje		2005
Obseg		str. 289-98
Jezik		eng
Abstrakt		We present BITOLA, an interactive literature-based biomedical discovery support system. The goal of this system is to discover new, potentially meaningful relations between a given starting concept of interest and other concepts, by mining the bibliographic database MEDLINE. To make the system more suitable for disease candidate gene discovery and to decrease the number of candidate relations, we integrate background knowledge about the chromosomal location of the starting disease as well as the chromosomal location of the candidate genes from resources such as LocusLink and Human Genome Organization (HUGO). BITOLA can also be used as an alternative way of searching the MEDLINE database. The system is available at http://www.mf.uni-lj.si/bitola/.
Deskriptorji		INFORMATION STORAGE AND RETRIEVAL MEDLINE GENETIC MARKERS DECISION MAKING, COMPUTER-ASSISTED GENES GENE POOL