Avtor/Urednik		Zadnik, Vesna
Naslov		Preživetje bolnic z rakom jajčnikov
Tip		monografija
Kraj izdaje		Ljubljana
Založnik		Univerza v Ljubljani, Medicinska fakulteta
Leto izdaje		1998
Obseg		str. 46
Jezik		slo
Abstrakt		Data from 282 patients who were first treated for epithelial ovarian malignoma at the Institute of Oncology and Gynecological clinic in Ljubljana between 1990 and 1992 were analyzed retrospectively. Twenty-one patients had borderline tumors and 259 had malignant ones. The patients were followed through 1997. The survival rates for malignant and borderline tumors were established and the influence of different prognostic factors on the survival of ovarian cancer patients was evaluated. The statistical method used was Kaplan - Meier method. The statistical significance of individual prognostic factors was examined using logrank test. The hazard ratio for each prognostic factor was established with Cox univariat analysis. The adjusted hazard ratios were calculated using Cox multivariate analysis for all prognostic factors. The five-year survival rate was 74% for border line patients and 38% for patients with carcinomas. The carcinoma patients died three-times more often than borderline tumor patients. The five-year survival-rates by stage (1 - 4) were as follows: 88%, -48%, 26% in 12%. The probability of dying with stage 4 is 21-times greater than stage 1. Older patients die frequently than younger ones (those older then 70 years are five-times more likely to die than those younger then 40). Five-year survival rates for older group were 12% and for the younger group 65%. Those older then 50 died 2,5 times often than those younger than 50. The five-year survival rate of those older than 50 is 31% compared with 61% in those younger than 50. In terms of cancer grades (1-3), the five-year survival rates are: 69%, 49%, 26%, respectively. Patients with grade three died three-times more frequently than those with grade l. The group with the diameter of residual implant after first surgery greater then 1 cm died five-times more often than the group with no macroscopic residual disease. (Abstract truncated at 2000 characters).
Deskriptorji		OVARIAN NEOPLASMS NEOPLASM STAGING SURVIVAL ANALYSIS