Avtor/Urednik		Prelević, GM; Kocjan, T; Markou, A
Naslov		Hormone replacement therapy in postmenopausal women
Tip		članek
Vir		Minerva Endocrinol
Vol. in št.		Letnik 30, št. 1
Leto izdaje		2005
Obseg		str. 27-36
Jezik		eng
Abstrakt		From the endocrine point of view, menopause is considered a deficiency state and menopausal hormone replacement therapy (HRT) regarded as restoring the premenopausal endocrine milieu. Millions of healthy postmenopausal women were taking HRT in late 1990's many in the absence of menopausal symptoms. The major benefit from HRT was considered to be cardiovascular protection and also protection against osteoporosis and Alzheimer's Disease. The Women's Health Initiative (WHI) trial and other studies published since 2002 fundamentally changed our understanding of risks and benefits associated with HRT. This review discusses the effects of HRT on menopausal symptoms, cognitive function, cardiovascular disease, osteoporosis and also breast and bowel cancer.
Deskriptorji		ESTROGEN REPLACEMENT THERAPY CARDIOVASCULAR DISEASES OSTEOPOROSIS BREAST NEOPLASMS COLORECTAL NEOPLASMS POSTMENOPAUSE