Avtor/Urednik		Arko, Darja
Naslov		Predoperativna ultrazvočna ocena globine invazije raka maternične sluznice
Tip		monografija
Kraj izdaje		Ljubljana
Založnik		Univerza v Ljubljani, Medicinska fakulteta
Leto izdaje		2005
Obseg		str. 64
Jezik		slo
Abstrakt		Treatment for cancer of the endometrium is primarily operative. The type and extent of the operation depends on the spread of the tumor, its histological type, degree of differentiation and depth of invasion into the uterine wall. The stated factors are indicators of the probability of cancer spread to the regional nodes and the grounds for eventual simultaneous removal of pelvic as well as paraaortal lymph nodes. Endometrial cancer is diagnosed by taking tissue samples during fractional abrasion or hysteroscopy. Thus we obtain data on the histological tumor type and degree of differentiation, but not on the depth of invasion into the uterine well. The aim of the present study was to evaluate the applicability of transvaginal ultrasound in assessing the depth of endometrial cancer invasion. In a prospective study, prior to surgery 157 patients were examined after fractional abrasion with histological confirmation of endometrial cancer. Ultrasonographic measurement of endometrial thickness was carried out and the depth of invasion evaluated as follows: no invasion, invasion of less than or more than half of the uterine wall. These results were compared with those of histopathological investigation of the removed uterus. The mean endometrial thickness, measured on the longitudinal section of the uterus at its thickest spot, was 17.1 mm, with a span of 1 - 50 mm. The ultrasonographic and histopathological evaluations of the depth of invasion were concordant in 102 (64.9%) patients. In 27 (17.2%) patients, ultrasonography evaluated an invasion smaller than that revealed by histopathology. In 28 (17.9%) patients, however, a larger invasion than shown by histopathotogy was evaluated. In the group of patients without invasion, the sensitivity of ultrasound was 38.9%, specificity 91.4%, PPV 36.8%, NPV 92.0 and reliability 85.4%. (Abstract truncated at 2000 characters)
Deskriptorji		ENDOMETRIAL NEOPLASMS HYSTEROSCOPY NEOPLASM INVASIVENESS NEOPLASM STAGING SENSITIVITY AND SPECIFICITY PROSPECTIVE STUDIES