Avtor/Urednik		Tomič, Viktorija; Šorli, Jurij; Trampuž, Andrej
Naslov		Ali je možno vzdrževati uspešen nadzor bolnišničnega širjenja MRSA v endemskem okolju?
Prevedeni naslov		Is it possible to maintain successful control of nosocomial spread of MRSA in a highly endemic setting?
Tip		članek
Vir		In: Berger T, Dobeic M, Vudrag M, editors. Preventiva pred širjenjem zoonoz in drugih nalezljivih bolezni v okolju. Zbornik referatov 2. interdisciplinarni simpozij DDD, zdravje in okolje z mednarodno udeležbo; 2004 okt 22; Ljubljana. Ljubljana: Slovenska veterinarska zveza, Sekcija za DDD in higieno okolja,
Leto izdaje		2004
Obseg		str. 67-72
Jezik		slo
Abstrakt		Objective: Aim of the study was to evaluate the feasibility of a strict infection control strategy to prevent cross-transmission of MRSA through a longer period of time in a 237-bed tertiary teaching hospital in a highly endemic area. Methods: From 1999 to 2001 we gradually built an infection control programme which in 2002 included consistent use of alcoholic hand rub instead of hand washing with soap and water, screening of admitted patients with risk factors for MRSA carriage (transfer from other hospitals' ICUs, transfer from nursing homes, surgery or repeated hospitalization in past year, previous colonization with MRSA), isolation and decolonization of MRSA carriers. Infection control programme stayed unchanged throughout 2003. Results:During 5 years period we detected 286 patients colonized or infected with MRSA and 1573 patients with MSSA. From 1999 - 2003 the incidence rate per 1000 admissions was 8.0, 7.7, 5.7, 6.8 and 8.5, respectively. Average age of patients with MRSA was 68.7, 66.7, 69.5, 72.3 and 72.5 in 1999, 2000, 2001, 2002 and 2003, respectively. Percentage of isolates classified as nosocomially acquired during stay in our hospital was 50, 45, 35, 6 and 18 in 1999, 2000, 2001, 2002 and 2003, respectively. From 1999 till 2003 we detected by active surveillance cultures 23%, 15%, 45%, 78% and 78% of MRSA carriers, respectively. Eleven patients acquired MRSA in our hospital and 5 of those were involved in an outbreak of previously unseen MRSA strain (resistant to mupirocin and rifampin). Three of those 5 patients were on a long term antimicrobial treatment for tuberculosis. Conclusion: In a country in which MRSA has been endemic, screening of patients with risk factors on admission and during a lengthy antimicrobial treatment, isolation and especially strict use of alcoholic hand rub is of great importance in preventing intrahospital transmission of MRSA.
Deskriptorji		STAPHYLOCOCCUS AUREUS STAPHYLOCOCCAL INFECTIONS HOSPITALIZATION CROSS INFECTION METHICILLIN RESISTANCE