| Avtor/Urednik | Meglič, A; Novljan, G; Rus, R; Kersnik-Levart, T | |
| Naslov | Kortikosteroidi pri zdravljenju bolezni sečil | |
| Prevedeni naslov | Steroid treatment in nephrology | |
| Tip | članek | |
| Vir | Slov Pediatr | |
| Vol. in št. | Letnik 12, št. 3 | |
| Leto izdaje | 2005 | |
| Obseg | str. 134-43 | |
| Jezik | slo | |
| Abstrakt | Among children and adolescents with urinary tract disorders steroids are most often used to treat patients with the nephrotic syndrome, less frequently in patients with nephritis in systemic lupus and patients with severe renal impairment caused by Henoch-Schonlein vasculitis or acute tubulointerstitial nephritis and rarely in patients with idiopathic membranoproliferative glomerulonephritis. The use of steroids in patients with the nephrotic syndrome, in which the entire treatment decision and prognosis of the disease are based on the response to steroid treatment, is described. In children and adolesecents after renal transplantation, steroids are used in conjunction with other immunosupressive agents during maintance treatment or alone in the treatment of the acute cellular rejection reaction. The most common side effects of steroid treatment in patients with urinary tract disorders are cited. In describing the different therapeutic schemes offered by foreign authors, the characteristics of steroid treatment in Slovenia are emphasised. | |
| Izvleček | Med otroki in mladostniki z boleznimi sečil, ki jih zdravimo s kortikosteroidi, so najpogosteje bolniki z nefrotskim sindromom, redkeje bolniki z nefritisom v okviru sistemskega lupusa, bolniki s hudo ledvično prizadetostjo zaradi Henoch-Schonleinovega vaskulitisa ali akutnega tubulointersticijskega nefritisa, izjemoma bolniki z idiopatskim membranoproliferativnim glomerulonefritisom. V članku opisujemo uporabo kortikosteroidov pri bolnikih z nefrotskim sindromom, pri katerih odločitev o celotnem zdravljenju in celo napoved izida bolezni temelji na odgovoru na steroidno zdravljenje. Pri otrocih in mladostnikih po presaditvi ledvice uporabljamo kortikosteroide skupaj z drugimi imunosupresivnimi zdravili v sklopu vzdrževalnega zdravljenja ali samostojno pri zdravljenju akutne celične zavrnitvene reakcije. Navajamo najpogostejše stranske učinke steroidnega zdravljenja pri nefroloških bolnikih. Pri opisovanju različnih terapevtskih shem po tujih avtorjih poudarjamo značilnosti zdravljenja pri nas. | |
| Deskriptorji | NEPHROTIC SYNDROME ADRENAL CORTEX HORMONES GLOMERULONEPHRITIS GLOMERULONEPHRITIS, MEMBRANOPROLIFERATIVE NEPHRITIS, INTERSTITIAL CHILD ADOLESCENCE KIDNEY TRANSPLANTATION |