Avtor/Urednik		Konttinen, YT; Wright, TM; Trebše, R; Takagi, M; Silbermann, M; Salo, J; Rieker, C; Pioletti, DP; Ogino, T; Nordsletten, L
Naslov		Total joint replacement and aseptic loosening
Tip		članek
Vir		Rheumatology
Vol. in št.		Letnik 8, št. 1
Leto izdaje		2006
Obseg		str. 98-102
Jezik		eng
Abstrakt		Total joint replacement reproduces a near normal joint function. Laminar flow, operation theatres, intravenous preoperative antibiotics and use of antibiotic cements decrease immediate and late infections. Improved implant biomaterial, surface finish and coating, and design and implant modularity, together with modern cementing and optimal surgical techniques, help ensure proper positioning of the implants. Long-term problems may be related to wear particles (which can be minimized with the use of hard-on-hard articulations or with highly cross-linked ultra-high molecular weight polyethylene), delayed type hypersensitivity, infections and/or poor initial fixation as a result of postoperative nonsteroidal antiinflammatory drugs (NSAIDs) use. Peri-implant bone resorption can be decreased with the use of bisphosphonates. Greater than 90% success rates can be achieved in the long term with joint replacement.
Deskriptorji		JOINT PROSTHESIS BIOMECHANICS PROSTHESIS FAILURE PROSTHESIS-RELATED INFECTIONS BACTERIAL INFECTIONS POLYETHYLENES HOST VS GRAFT REACTION DIPHOSPHONATES HYPERSENSITIVITY, DELAYED