Avtor/Urednik     Grošelj, Urh; Kavčič, Marko
Naslov     Vpliv nadzorovane podhladitve na zdravljenje bolnikov po srčnem zastoju
Tip     monografija
Kraj izdaje     Ljubljana
Založnik     Univerza v Ljubljani, Medicinska fakulteta
Leto izdaje     2005
Jezik     slo
Abstrakt     Background. Cardiac arrest is the most common cause of sudden natural death. Survival rates after cardiac arrest are low and have remained roughly unchanged over the years. Ischemia during cardiac arrest and reperfusion damage after resuscitation are often the source of permanent neurological impairment in survivors. For a long time, treatment of cardiac arrest has been focused primarily on resuscitation procedures and supportive treatment of these patients. It was only controlled hypothermia that opened the possibility of effective causal prevention of neurological damage. Induced hypothermia has been used as a standard treatment at the Center for Intesive Internal Medicine (CIIM) since year 2004. Aim. The purpose of our study was to evaluate the survival, neurological outcome and safety of controlled hypothermia. Our intention was to check yet unpublished clinical observations on slower neurological progress of patients who undergo hypothermia during their treatment at the CIIM. Hypotheses. Controlled hypothermia improves neurological outcomes and survival and does not increase the incidence of treatment complications in patients after cardiac arrest treated at the CIIM. In patients who regain consciousness, the time from cardiac arrest to the time when it is possible to have sensible contact with the patient is longer in the group treated with controlled hypothermia. Methods. We included patients who were treated at the CIIM in the period from 1 January 2001 to 29 April 2005 following primary cardiac arrest. All enrolled patients fulfilled the criteria for treatment with controlled hypothermia. The test group consisted of all patients treated after 1 January 2004, when controlled hypothermia was adopted as the standard treatment method and the control group included all other patients from the observed time period. (Abstract truncated at 2000 characters)
Deskriptorji     HEART ARREST
HYPOTHERMIA, INDUCED
CARDIOPULMONARY RESUSCITATION
NEUROLOGIC EXAMINATION
EMERGENCY SERVICE, HOSPITAL
SURVIVAL ANALYSIS