Avtor/Urednik		Skiljević, Dusan; Nikolić, Milos; Milinković, Mirjana; Bonaci-Nikolić, Branka
Naslov		Regressing anaplastic CD30-positive large-cell lymphoma of the skin
Tip		članek
Vir		Acta Dermatovenerol Alp Pannon Adriat
Vol. in št.		Letnik 15, št. 3
Leto izdaje		2006
Obseg		str. 131-4
Jezik		eng
Abstrakt		Originally believed to be of histiocytic origin, regressing primary cutaneous anaplastic large-cell lymphoma is a CD30 (Ki 1) positive T-cell lymphoma with histologic high grade malignancy, but with an often favorable clinical course with regression of individual lesions. We present a case of a 69-year-old white woman with an 8-month history of noduloulcerative lesions on her right lower leg, otherwise in good general health. The clinical, histologic, and immunohistochemical findings pointed to CD30 positive primary cutaneous anaplastic large-cell lymphoma. There were no signs of generalization, lymph node or internal organ involvement. After 2 years of activity, the disease regressed. During the 10-year follow-up period, no signs of disease reactivation were noted. Accurate recognition of this lymphoma is important to avoid unnecessary aggressive treatments.
Deskriptorji		SKIN NEOPLASMS LYMPHOMA, LARGE-CELL, KI-1 AGED