| Avtor/Urednik | Sočan, Maja; Novak-Mlakar, Dominika; Ogrin-Rehberger, Petra | |
| Naslov | Pasavec - dostopni epidemiološki podatki v Sloveniji | |
| Prevedeni naslov | Herpes zoster - available epidemiological data in Slovenia | |
| Tip | članek | |
| Vir | Zdrav Vestn | |
| Vol. in št. | Letnik 75, št. 9 | |
| Leto izdaje | 2006 | |
| Obseg | str. 555-60 | |
| Jezik | slo | |
| Abstrakt | Background Herpes zoster results from reactivation of latent varicella zoster virus (VZV) in dorsal nerve ganglia. Herpes zoster is characterized by a painful dermatomal vesicular rash. Reactivation results from impaired cell-mediated immunity. The determinants of reactivation in individuals with no underlying immunosuppression are poorly understood. The introduction of vaccination against varicella is expected to lower the incidence rate of chickenpox The influence of vaccination on herpes zoster morbidity is not clear and demands enhanced surveillance. Before the introduction of vaccination, the available epidemiological data should be analyzed for the availability, value and shortcomings. Methods The data from two electronic data-sets of Institute of Public Health of the Republic Slovenia were analysed: notified cases and number of consultations on primary level for herpes zoster - »ZUBSTAT« (data set of all first visits in primary care, Institute of Public Health of the Republic Slovenia). The data were stratified by age and sex. The hospitalization data were extracted from Eletronic data set for diseases which require hospitalization (entitled BOLOB, IPH). For notified and hospitalized cases also the month when shigles appeared was available. Results The number of notified cases increased steadily from year 1995 when mandatory reporting has been implemented. In year 2005 the incidence rate rose to 74/100,000. Approximately a quarter of cases (23.4%) was 70 years of age or older. According to the second data-set, which encompasses first visits in primary care, 5891 to 6527 patients were coded as herpes zoster. The incidence rate increases with age, being highest after age of 65 years (675 to 760/100,000). Women have higher incidence rate of herpes zoster in almost all age groups. The distribution of notified cases suggests seasonal peak in summer. The highest number of admissions was in September and October. (Abstract truncated at 2000 characters) | |
| Izvleček | Izhodišča Pasavec je posledica reaktiviranja latentne okužbe z virusom varicela-zoster v dorzalnih ganglijih in poteka z značilno klinično sliko - bolečimi mehurčki, ki pokrivajo najmanj en dermatom. Osebe z motnjo celično posredovane imunosti pogosteje zbolevajo za pasavcem. Determinante reaktiviranja v večini primerov, ko ni motenj imunosti, niso jasne. Uvedba cepljenja otrok z živim oslabljenim cepivom zmanjšuje pojavnost noric. Ni jasno, kako bo precepljenost vplivala na zbolevnost s pasavcem, kar bo potrebno pozorno spremljati. Zato je potrebno pred uvedbo cepljenja poznati dostopne epidemiološke podatke, njihovo vrednost, slabosti in omejitve. Metode Zbrali smo podatke o prijavljenih primerih pasavca od leta 1995 da je (začetek obvezne prijave). Podatke o prvih obiskih pri zdravniku na primarni ravni zaradi pasavca smo poiskali v podatkovni zbirki ZUBSTAT (Zbirka podatkov o »obiskih in napotitvah« v zunajbolnišničnem zdravstvenem varstvu, Inštitut za varovanje zdravja RS). Podatke o hospitalizacijah smo pridobili v podatkovni zbirki BOLOB (Podatkovne zbirke o bolnišničnih obravnavah zaradi bolezni, Inštitut za varovanje zdravja). Podatki so obsegali spol in starostno skupino, mesec zbolenja pri prijavljenih primerih in mesec sprejema pri bolnišničnih obravnavah. Rezultati Od začetka prijavljanja leta 1995 se je število prijavljenih primerov povečevalo. Prijavna incidenčna stopnja je bila v letu 2005 že 74/100.000. Slaba četrtina prijav (23,4%) so bili bolniki, starejši od 70 let. Po podatkih podatkovne zbirke ZUBSTAT je zaradi pasavca obiskalo zdravnika od 5891 do 6527 bolnikov letno. Zbolevnost narašča s starostjo, najvišja je pri starejših od 65 let (675 do 760/100.000). V skoraj vseh starostnih skupinah so več obolevale ženske kot moški. Po podatkih zbirke prijavljenih primerov se je nakazovalo večje zbolevanje v poletnih mesecih. Največ hospitalizacij je bilo septembra in oktobra. (Izvleček skrajšan pri 2000 znakih) | |
| Deskriptorji | HERPES ZOSTER DISEASE NOTIFICATION HERPESVIRUS 3, HUMAN INCIDENCE SEASONS AGE FACTORS SEX FACTORS HOSPITALIZATION SLOVENIA |