Avtor/Urednik     Štor, Z; Juvan, R; Jelenc, F; Repše, S
Naslov     Treatment results of colorectal cancer - 10-years series of UMC Ljubljana (1991-2000)
Tip     članek
Vir     Acta Chir Iugosl
Vol. in št.     Letnik 13, št. 2
Leto izdaje     2006
Obseg     str. 103-7
Jezik     eng
Abstrakt     In Slovenia the incidence of colorectal cancer is growing rapidly. In 1998 1022 new cases were registered. Our study compares results of two groups of patients with colorectal cancer. Patients and methods. In the period from 1.1.1991 to 31.12.2000 1478 patients with a colorectal carcinoma underwent potentially curative resection. We divided them in two groups, one operated in the first 5-years and second in later 5-years period. 5years survival was estimated with Kaplan-Meier statisdcal analysis. Parients who died within 30 days after the operation were censored. Differences in survival curves behveen both groups were assessed by the log rank test. Results. We resected 1478/1599 (92,4%) patients. There was 913 (61,7%) patients resected with colon cancer and 528 (35,8%) with rectal cancer and 37 (2,5%) with sinhronius tumors. R0 resection was performed in 1174 (79,4%) patients, R1 in 29 (2,0%), and R2 in 273 (18,5%) patients. Postoperative mortality rate in resected patients was 5,48% (81/1478), in the group with paliative operations was 17,35% (21/121). Overall five-years survival rate was 54,9% (56,18% for colon cancer and 52,4% for rectal cancer). Five-years survival rate for the patients with radical resection (R0) was 66,54% for colon cancer and 59,47% for rectal cancer. Conclusion. 5-years survival for R0-resected patients with colon cancer was in the last period from 1996 to 2000 statistically significantly better compared with the period from 1991 to 1995 (76% vs 60%) in stage I (p=0,04048) and in stage III (p=0,01842). 5-years survival for R0-resected patients with rectal cancer was significantly better in the same period (63% vs 55%) (p= 0,03627) in stage III (p=0,01663).
Deskriptorji     COLORECTAL NEOPLASMS
SURVIVAL ANALYSIS
TREATMENT OUTCOME