Avtor/Urednik		Tekauc-Golob, A; Burja, S
Naslov		Kakovost življenja otrok, rojenih z znaki intrauterino zastale rasti
Prevedeni naslov		Quality of life of small for gestation age infants
Tip		članek
Vir		Slov Pediatr
Vol. in št.		Letnik 13, št. Suppl 1
Leto izdaje		2006
Obseg		str. 204-9
Jezik		slo
Abstrakt		Background. Intrauterine growth retardation (IUGR) is a strong risk factor forimpaired neurodevelopmental outcome. Although several factors that induce IUGR are well known, all the influences on abnormal development of the central nervous system have yet to be clarified. The key to clarification is monitoring the development of SGA children till school entry and beyond. Patients and methods. In a preliminary study the neurodevelopmental and cognitive outcome were prospectively followed in a group of 74 small for gestational age (SGA) infants who were part of a group of 300 infants at high risk of impaired neurodevelopmental outcome. Clinical examination and brain ultrasound (US) after birth, US examination at 6 months and clinical and neurodevelopmental examination at one and two years of age were performed. The data were statistically evaluated. Results. Various degrees of abnormal neurodevelopmental and US findings were found in the group of SGA children. Normal outcome at two years was found in 46% of those children. Conclusions. The optimal time to deliver IUGR infants remains difficult to assess. More investigations and further follow-up of neurological and cognitive development of SGA infants is needed to evaluate their quality of life.
Izvleček		Izhodišča. V skupini zahiranih novorojenčkov je močno povečano tveganje oškodovanosti centralnega živčnega sistema. Poznamo najpogostejše dejavnike, povezane z razvojem intrauterino zavrte rasti ploda, vendar vsi vplivi na moten razvoj centralnega živčevja še niso razjasnjeni. Ključ do razjasnitve je spremljanje razvoja zahirančkov do začetkov šolske dobe in še dlje. Preiskovanci in metode. V preliminarni študiji smo pri skupini 300 izbranih novorojenčkov z visoko stopnjo tveganja za motnje v nevrološkem in kognitivnem razvoju prospektivno sledili razvoju 74 intrauterino zahiranih otrok. Diagnostična obravnava je vsebovala klinični pregled po rojstvu, ultrazvočni pregled možganov, ponoven ultrazvočni pregled možganov pri starosti 6 mesecev ter klinični pregled in testiranje razvoja kognitivnih funkcij v starosti enega do dveh let. Podatke smo statistično obdelali. Rezultati. Ugotavljali smo različne stopnje odstopanj od normalnega razvoja, ki so se razlikovali glede na dejavnike tveganja. Normalen izvid razvojnega pregleda je pri dveh letih izkazovalo 46% vseh otrok iz skupine zahirančkov. Zaključki. Za ocenjevanje kakovosti življenja ob rojstvu zahiranih otrok so potrebne nadaljnje raziskave in dolgotrajnejše sledenje nevrološkega in kognitivnega razvoja teh otrok.
Deskriptorji		FETAL GROWTH RETARDATION CHILD DEVELOPMENT BRAIN COGNITION DISORDERS QUALITY OF LIFE INFANT, NEWBORN INFANT