Avtor/Urednik		Kraigher, Alenka; Bregant, Lev
Naslov		BCG in nova cepiva proti tuberkulozi
Prevedeni naslov		BCG and new vaccines against tuberculosis
Tip		članek
Vir		In: Felc Z, Ilijaš-Trofenik A, Bovha K, editors. Tuberkuloza pri nosečnici, novorojenčku in otroku. Krči pri novorojenčku in dojenčku. Zbornik predavanj 4. simpozij in učna delavnica z mednarodno udeležbo Na stičiščih neonatologije; 2006 nov 17-18; Laško. Celje: Splošna bolnišnica Celje,
Leto izdaje		2006
Obseg		str. 81-90
Jezik		slo
Abstrakt		Tuberculosis remains a major health threat, solved by neither chemotherapy nor vaccination is still considered an important strategy. BCG vaccination is still the subject of much controversy as to its effectiveness and applicability. BCG vaccination does not prevent transmission of infection to the individual. Although several new vaccine candidates will pass clinical trials within the next years, the most effective vaccination strategy will be to combine different vaccine candidates and to use a prime-boost approach. A successful vaccination regime must stimulate memory T cells and, at the same time, avoid exhaustion of memory and suppression by regulatory mechanisms. The most probable scenario is priming with one vaccine candidate followed by boosting with another vaccine candidate.
Deskriptorji		TUBERCULOSIS BCG VACCINE