Avtor/Urednik		Poredoš, P; Ježovnik, MK
Naslov		Does effect of preventive measures depend on location of the atherosclerotic process?
Tip		članek
Vir		In: Belch JJF, editor. EUROCHAP. Proceedings of the 16th European chapter congress of the International union of angiology; 2005 Oct 25-27; Glasgow. Bologna: Medimond,
Leto izdaje		2005
Obseg		str. 37-41
Jezik		eng
Abstrakt		Atherosclerosis is considered as generalized disease, therefore patients with clinical manifesCation of a particular atherosclerotic disease are likely to have concomitant preclinieal or clinical atherosclcrotic lesions in other vascular beds. As pathomorphological characteristics of atherosclerotic plaques in different locarions are similar, most probably similar or identical ethiopathogenetic mechanisms are involved in different atherosclerotic diseases. Therefore the effect of treatment of risk factors on atherosclerotic lesions in different parts of a vascular system is expected. In the last decade the data from different trials have indicated that treatment of patients with antiplatelet drugs, statins and ACE inhibitors prevents the progression of local disease, reduces car3iavascular events and improves prognosis of atherosclerotic disease. While a great emphasis has been placed on the aggressive pharmacological management of coronary artery disease, less attention has been devoted to the pharmacological management of cerebrovascular and much less to peripheral arterial disease: despite their significant morbidity and mortality. The data from clinical trials and from subgroup analyses have shown that elimination of risk factors for atherosclerosis reduces cardiovascular events and improves prognosis in coronary cerebrovascular and peripheral arterial occlusive disease. However there are some data that the effect of preventive procedures is to some extent dependent on different locations of atherosclerotic disease.
Deskriptorji		ATHEROSCLEROSIS ANTILIPEMIC AGENTS PLATELET AGGREGATION INHIBITORS ANTIHYPERTENSIVE AGENTS